Portfolio

ChemBridge offers an extensive off-the-self chemistry platform for discovery chemistry programs including:

	700,000 screening compounds consisting of both collected and combinatorial molecules
	Medicinally relevant Building Blocks
	Hit2Lead.com online chemical store

Collected Screening Libraries - Over 450,000 handcrafted small molecule compounds in stock with new compounds added annually. Our stock compounds are selected using novelty, diversity and druglike property analysis medicinal chemistry expertise.

Combinatorial Libraries – Over 200,000 compounds designed and synthesized in-house to explore pharmacophore space using proprietary building blocks and unpublished novel scaffolds. New compounds added anually.

Building Blocks Collection - A collection of commercially available reagents for the synthesis of advanced molecules for hit-to-lead and lead optimization programs. Over 8,000 Building Blocks are available off the shelf in 1-25g amounts. Over 95% purity by NMR and LCMS is guaranteed on all Building Blocks.

Successful Track Record

Experience - 15 years of excellence as a chemistry service provider/partner, including major, multi-year alliances with top pharmaceutical companies. Click here to view Press Releases

Deliverability - over 10 million samples provided to more than 350 satisfied clients worldwide, including all major pharmaceutical companies.  Consistent delivery against CRO project deadlines.

Advanced Leads - obtained by our clients in a variety of HTS programs; numerous examples of success and discoveries published in premier journals, such as Science, Nature Cell Biology, JACS, PNAS, JBC, Cancer Res., etc. Click here to view Publications

Innovations - continuous establishment of new industry standards:

	1995:  Pioneered 3D pharmacophore diversity analysis in compound collections design (DIVERSet™)
	1996:  100% QC guarantee and 100% bar-code-based sample processing
	1998:  Therapeutic area focused screening set (CNS-Set™)
	2000:  DMSO pre-plated sets with druglike properties (MicroFormats™)
	2000:  The design and synthesis of novel templates leading to the PHARMACophore library
	2005:  Leadlike diverse library with improved properties (NOVACore Library)
	2002/2008:  Targeted and focused libraries based on the 3D pharmacophore design
	Creative top tier chemists producing unique lead discovery libraries & offering medicinal chemistry support.

For more information contact sales@chembridge.com.

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