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ChemBridge Corporation Signs New Discovery Chemistry Strategic Alliance Agreement with Merck & Co., Inc.

San Diego, California, December 7, 2004, -- ChemBridge Corporation announced today that it has signed a five-year discovery chemistry collaboration agreement with Merck & Co., Inc. This new alliance follows a previous research collaboration of Merck with ChemBridge Corporation and ChemBridge Research Laboratories, Inc. (CRL) that was established in 2001.

Under the latest agreement, which expands and extends ChemBridge and Merck's alliance through 2009, ChemBridge FTE scientists will work with Merck's scientists on multiple research intensive discovery chemistry projects in support of Merck's global drug discovery efforts. Financial terms of the agreement were not disclosed.

“Through our collaboration, ChemBridge Corporation and CRL were able to execute on very complex chemistry and always exceeded our expectations,” said Steven Hutchins, Director of Outsourcing at Merck. “This new collaboration will build upon our past successful interactions, which included custom lead generation libraries and other projects, and is expected to enable Merck to advance our discovery efforts in key areas.”

“This latest agreement builds upon and extends our 10-year relationship with Merck, and is a credit to the skills and dedication of many ChemBridge and CRL scientists,” said Eugene Vaisberg, Chairman & CEO of ChemBridge Corporation and CRL. “Our continuing relationship with Merck is an important milestone in ChemBridge's strategy to establish itself as “the gold standard” in discovery chemistry outsourcing. At the same time, CRL will continue to shift its focus toward medicinal chemistry research collaborations and internal drug discovery programs.”

ChemBridge Corporation is a leading global discovery chemistry CRO. Privately-held, ChemBridge was founded in Chicago in 1993 and has grown, self-funded, to a global company with 350 employees with an impeccable track record of quality and deliverability. ChemBridge has its corporate headquarters in San Diego, European offices in the UK, a marketing agency in Japan, and operates a large, state-of-the-art offshore discovery chemistry research site in Moscow, Russia. Over 400 pharmaceutical and biotech companies and universities worldwide have taken advantage of ChemBridge's portfolio of advanced discovery chemistry services and products including its library of 600,000 diverse drug-like small molecule compounds.

ChemBridge Research Laboratories, Inc. (CRL), www.chembridgeresearch.com, is a chemistry-based small molecule drug discovery company founded in 2000 as a spin-off of ChemBridge Corporation. Located in San Diego, in custom built, state-of-the-art research facilities, privately held CRL has 58 employees including 48 scientists (31 Ph.D.) led by research management with substantial experience in the pharmaceutical and biotech industry. CRL is focused on collaborative medicinal chemistry support, hit-to-lead and lead optimization programs, and has a track record of consistently exceeding the goals on all its research collaborations including major multi-year alliances with Pfizer, Inc. and Merck & Co. CRL's internal drug discovery efforts leverage the company's comprehensive medicinal chemistry platform and its core expertise in kinase and GPCR areas and encompass one obesity and two oncology programs.

Contact:
ChemBridge Corporation
ChemBridge Research Laboratories, Inc. (CRL)
Eugene Vaisberg
Chairman & CEO
Phone: 1-858-451-7400, ext. 110

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