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Collected Screening Libraries
Combinatorial Libraries
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PRODUCTS: OVERVIEW & KEY FACTS

Portfolio

ChemBridge offers an extensive off-the-shelf chemistry platform for discovery chemistry programs including:

700,000 small molecule screening compounds consisting of both collected and combinatorial molecules
Medicinally relevant chemical Building Blocks
Hit2Lead.com online chemical store

Chemical Libraries

Collected Screening Libraries - This collection of small molecule screening compounds contains over 450,000 handcrafted small molecule compounds in stock with new compounds added annually. Our stock compounds are selected using novelty, diversity, druglike property analysis, and medicinal chemistry expertise.

Click here for a table of ChemBridge ID’s for published compounds.

Combinatorial Libraries – This NOVACore chemical library along with the PHARMACophore Library and GPCR Library total over 200,000 compounds designed and synthesized in-house to explore pharmacophore space using proprietary building blocks and unpublished novel scaffolds. New compounds added annually.

Building Blocks Collection - Our chemical building block  collection contains commercially available reagents for the synthesis of advanced molecules for hit-to-lead and lead optimization programs. Over 10,000 Building Blocks are available off the shelf in 1-25g amounts. Over 95% purity by NMR and LCMS is guaranteed on all Building Blocks.

Successful Track Record

Experience - 15 years of excellence as a chemistry service provider/partner, including major, multi-year alliances with top pharmaceutical companies. Click here to view Press Releases

Deliverability - over 10 million samples provided to more than 350 satisfied clients worldwide, including all major pharmaceutical companies.  Consistent delivery against CRO project deadlines.

Advanced Leads - obtained by our clients in a variety of HTS programs; numerous examples of success and discoveries published in premier journals, such as Science, Nature Cell Biology, JACS, PNAS, JBC, Cancer Res., etc. Click here to view Publications

Innovations - continuous establishment of new industry standards:

1995:  Pioneered 3D pharmacophore diversity analysis in compound collections design (DIVERSet™)
1996:  100% QC guarantee and 100% bar-code-based sample processing

1998:  Therapeutic area focused screening set (CNS-Set™)

2000:  DMSO pre-plated sets with druglike properties (MicroFormats™)
2000:  The design and synthesis of novel templates leading to the PHARMACophore library
2005:  Leadlike diverse library with improved properties (NOVACore Library)
2002/2008:  Targeted and focused libraries based on the 3D pharmacophore design
Creative top tier chemists producing unique lead discovery libraries & offering medicinal chemistry support.

For more information on our chemical libraries or our chemical building block collection, contact sales@chembridge.com.

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