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2001-2002 Research Articles Citing ChemBridge

Below is a partial list of articles citing the use of ChemBridge libraries and compounds. The list is updated as additional articles are identified. The PMID value can be used to link to the record at the PubMed website.

  • Development of a solid-phase binding assay and identification of nonpeptide ligands for the FynB Src homology 2 domain. Journal of Pharmaceutical and Biomedical Analysis 2002. PMID 11682210
  • A small-molecule inhibitor of skeletal muscle myosin II. Nature Cell Biology 2002. PMID 11744924
  • A Novel Approach for Characterizing Protein Ligand Complexes: Molecular Basis for Specificity of Small-Molecule Bcl-2 Inhibitors. Journal of the American Chemical Society 2002. PMID 11841292
  • Heuristics for Similarity Searching of Chemical Graphs Using a Maximum Common Edge Subgraph Algorithm. Journal of Chemical Information and Computer Sciences 2002. PMID 11911700
  • Inhibition of Protein-Protein Association by Small Molecules: Approaches and Progress. Journal of Medicinal Chemistry 2002. PMID 11931608
  • High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter . Carcinogenesis 2002. PMID 12082016
  • A small-molecule inhibitor of the ribonucleolytic activity of human angiogenin that possesses antitumor activity. Proceedings of the National Academy of Sciences 2002. PMID 12118120
  • High-affinity Activators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Chloride Conductance Identified by High-throughput Screening. Journal of Biological Chemistry 2002. PMID 12161441
  • Small molecule modulation of Smoothened activity. Proceedings of the National Academy of Sciences 2002. PMID 12391318
  • Small molecule modulation of Smoothened activity . Proceedings of the National Academy of Sciences 2002. PMID 12391318
  • Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI . Proceedings of the National Academy of Sciences 2002. PMID 12438696
  • Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI. Proceedings of the National Academy of Sciences 2002. PMID 12438696
  • Automated Colorimetric Screen for Apyrase Inhibitors. BioTechniques 2002. PMID 12449379
  • Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion. Journal of Clinical Investigation 2002. PMID 12464670
  • Identification of Bioactive Molecules by Adipogenesis Profiling of Organic Compounds. Journal of Biological Chemistry 2002. PMID 12496288
  • Identification of bioactive molecules by adipogenesis profiling of organic compounds. Journal of Biological Chemistry 2002. PMID 12496288
  • An Overview of the Diversity Represented in Commercially-Available Databases. Molecular Diversity 2002. PMID 12549670
  • How to Acquire New Biological Activities in Old Compounds by Computer Prediction. Other 2002. PMID 12825794
  • Reactions of N,N-bis(siloxy)enamines with trimethylsilyl cyanide: aliphatic nitro compounds as convenient precursors of 5-aminoisoxazoles. Mendeleev Communications 2002. PMID N/A
  • Rapid Preparation of Glycolipid Libraries by Cross Metathesis. Other 2002. PMID
  • Combinatorial Chemistry. Other 2002. PMID
  • Study of the Products of Reaction of 5-Azauracil with Malondiamide and Aromatic C-Nucleophiles. Other 2002. PMID
  • Structure-Activity Studies of Substituted Quinoxalinones as Multiple-Drug-Resistance Antagonists. Journal of Medicinal Chemistry 2001. PMID 11170649
  • Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL. Nature Cell Biology 2001. PMID 11175750
  • High-Throughput Drug Screening of the DPC4 Tumor-Suppressor Pathway in Human Pancreatic Cancer Cells. Annals of Surgery 2001. PMID 11323508
  • Chemical genomics: what will it take and who gets to play?. Genome Biology 2001. PMID 11423004
  • Lead compounds discovered from libraries. Current Opinion in Chemical Biology 2001. PMID 11479119
  • Identification of a Class of Small Molecule Inhibitors of the Sirtuin Family of NAD-dependent Deacetylases by Phenotypic Screening. Journal of Biological Chemistry 2001. PMID 11483616
  • Use of isogenic human cancer cells for high-throughput screening and drug discovery. Nature Biotechnology 2001. PMID 11581659
  • Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul . Current Biology 2001. PMID 11591315
  • Small molecules that dramatically alter multidrug resistance phenotype by modulating the substrate specificity of P-glycoprotein. Proceedings of the National Academy of Sciences 2001. PMID 11707575
  • Synthesis of tetrasubstituted thiophenes on solid-support using the Gewald reaction. Tetrahedron Letters 2001. PMID N/A
  • Stable sigma-adducts of 5-azauracil with C-nucleophiles. Mendeleev Communications 2001. PMID N/A
  • Computer-Aided Search for Potential Drugs Exhibiting a Combined Antihypertensive Effect. Other 2001. PMID
  • Probing adenosine and P2 receptors: Design of novel purines and nonpurines as selective ligands. Other 2001. PMID
  • Innovative Stoffgemische. Book Chapter 2001. PMID