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2005-2006 Research Articles Citing ChemBridge

Below is a partial list of articles citing the use of ChemBridge libraries and compounds. The list is updated as additional articles are identified. The PMID value can be used to link to the record at the PubMed website.

  • CB694, a Novel Antimitotic With Antitumor Activities. International Journal of Cancer 2006. PMID 16152590
  • Kinase inhibitor recognition by use of a multivariable QSAR model. Journal of Molecular Graphics and Modelling 2006. PMID 16253531
  • Antitumor Activity and Downregulation of Pro-Angiogenic Molecules in Human Prostate Cancer Cells by a Novel Thiazolidione Compound. Other 2006. PMID 16302260
  • A credit-card library approach for disrupting protein-protein interactions. Bioorganic and Medicinal Chemistry Journal 2006. PMID 16384710
  • Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature 2006. PMID 16400329
  • In silico identification of novel EGFR inhibitors with antiproliferative activity against cancer cells. Bioorganic and Medicinal Chemistry Letters 2006. PMID 16413185
  • Support Vector Machines in HTS Data Mining: Type I MetAPs Inhibition Study. Journal of Biomolecular Screening 2006. PMID 16418315
  • The First Potent Inhibitors for Human Glutaminyl Cyclase: Synthesis and Structure-Activity Relationship. Journal of Medicinal Chemistry 2006. PMID 16420052
  • Target structure-based discovery of small molecules that block human p53 and CREB binding protein association. Chemistry and Biology 2006. PMID 16426974
  • Design and Synthesis of 5-Aryl-pyridone-carboxamides as Inhibitors of Anaplastic Lymphoma Kinase. Journal of Medicinal Chemistry 2006. PMID 16451066
  • Novel Human Lipoxygenase Inhibitors Discovered Using Virtual Screening with Homology Models. Journal of Medicinal Chemistry 2006. PMID 16480270
  • Identification of Small Molecules that Sensitize Resistant Tumor Cells to Tumor Necrosis Factor-Family Death Receptors . Cancer Research 2006. PMID 16489043
  • A High-Throughput Cell-Based Assay for Inhibitors of ABCG2 Activity. Journal of Biomolecular Screening 2006. PMID 16490770
  • Selective Anti-Cytomegalovirus Compounds Discovered by Screening for Inhibitors of Subunit Interactions of the Viral polymerase. Chemistry and Biology 2006. PMID 16492567
  • Stabilization of the Activated alphaMbeta2 Integrin by a Small Molecule Inhibits Leukocyte Migration and Recruitment. Biochemistry 2006. PMID 16503641
  • Identification of Novel Parasitic Cysteine Protease Inhibitors by Use of Virtual Screening. 2. The Available Chemical Directory. Journal of Medicinal Chemistry 2006. PMID 16509575
  • Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases. Proceedings of the National Academy of Sciences 2006. PMID 16537516
  • Novel Compound 2-Methyl-2H-pyrazole-3-carboxylic Acid (2-methyl-4-o-tolylazo-phenyl)-amide (CH-223191) Prevents 2,3,7,8-TCDD-Induced Toxicity by Antagonizing the Aryl Hydrocarbon Receptor. Molecular Pharmacology 2006. PMID 16540597
  • Characterization of voltage-gated sodium-channel blockers by electrical stimulation and fluorescence detection of membrane potential. Nature Biotechnology 2006. PMID 16550174
  • Structural analysis of metalloform-selective inhibition of methionine aminopeptidase. Acta Crystallographica - All Sections 2006. PMID 16552144
  • Relationships between Molecular Complexity, Biological Activity, and Structural Diversity. Journal of Chemical Information and Modeling 2006. PMID 16562980
  • Structure-Based Pharmacophore Design and Virtual Screening for Novel Angiotensin Converting Enzyme 2 Inhibitors. Journal of Chemical Information and Modeling 2006. PMID 16563001
  • Biochemical suppression of small molecule inhibitors: a new strategy to identify inhibitor targets and signaling pathway components. Chemistry and Biology 2006. PMID 16632257
  • Antitumor Activity of Sphingosine Kinase Inhibitors. The Journal of Pharmacology and Experimental Therapeutics 2006. PMID 16632640
  • Substituted 2-phenyl-benzimidazole derivatives: novel compounds that suppress key markers of allergy. European Journal of Medicinal Chemistry 2006. PMID 16647159
  • Bioinformatics Platform Development: From Gene to Lead Compound. Select Journal Title 2006. PMID 16671411
  • A small-molecule screen in C. elegans yields a new calcium channel antagonist. Nature 2006. PMID 16672971
  • Polymer-Supported Synthesis of Pyridone-Focused Libraries as Inhibitors of Anaplastic Lymphoma Kinase. Journal of Combinatorial Chemistry 2006. PMID 16677010
  • The Cdc42 inhibitor secramine B prevents cAMP-induced K+ conductance in intestinal epithelial cells. Biochemical Pharmacology 2006. PMID 16677615
  • Obtaining and screening compound collections: a user\'s guide and a call to chemists. Current Opinion in Chemical Biology 2006. PMID 16677847
  • Evolution of the Thienopyridine Class of Inhibitors of IkappaB Kinase-Beta: Part I: Hit-to-Lead Strategies. Journal of Medicinal Chemistry 2006. PMID 16686533
  • Identification of TRIO-GEFD1 chemical inhibitors using the yeast exchange assay. Biology of the Cell 2006. PMID 16686599
  • Discovery of small molecule inhibitors of West Nile virus using a high-throughput sub-genomic replicon screen. Antiviral Research 2006. PMID 16724398
  • Dynasore, a Cell-Permeable Inhibitor of Dynamin. Developmental Cell 2006. PMID 16740485
  • The Discovery of New 11Beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitors by Common Feature Pharmacophore Modeling and Virtual Screening. Journal of Medicinal Chemistry 2006. PMID 16759088
  • Discovery of a Novel Family of SARS-CoV Protease Inhibitors by Virtual Screening and 3D-QSAR Studies. Journal of Medicinal Chemistry 2006. PMID 16759091
  • Selective inhibitors of bacterial DNA adenine methyltransferases. Journal of Biomolecular Screening 2006. PMID 16760373
  • Chemical Genetics. Chemical Reviews 2006. PMID 16771457
  • 3-Arylimino-2-indolones Are Potent and Selective Galanin GAL3 Receptor Antagonists. Journal of Medicinal Chemistry 2006. PMID 16789730
  • Identification of novel antimicrobials using a live animal infection model. Proceedings of the National Academy of Sciences 2006. PMID 16801562
  • Separation and Characterization of Caveolae Subclasses in the Plasma Membrane of Primary Adipocytes; Segregation of Specific Proteins and Functions. Other 2006. PMID 16803459
  • A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding. Science Signaling 2006. PMID 16804159
  • Artery/vein specification is governed by opposing phosphatidylinositol-3 kinase and MAP kinase/ERK signaling. Current Biology 2006. PMID 16824925
  • A High-Throughput Drug Screening System for HIV-1 Transcription Inhibitors. Journal of Biomolecular Screening 2006. PMID 16831859
  • Screening-based discovery and structural dissection of a novel family 18 chitinase inhibitor.. Journal of Biological Chemistry 2006. PMID 16844689
  • FAF-Drugs: free ADME/tox filtering of compound collections. Nucleic Acids Research 2006. PMID 16845110
  • Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds. Journal of Biomolecular Screening 2006. PMID 16858005
  • Using High-Throughput Screening Data To Discriminate Compounds with Single-Target Effects from Those with Side Effects. Journal of Chemical Information and Modeling 2006. PMID 16859287
  • Small Molecule Inhibitor of p53 Binding to Mitochondria Protects Mice from Gamma Radiation. Nature Chemical Biology 2006. PMID 16862141
  • Nucleophilic Group Transfer Reactivity for Fibric Acid Derived Drug Molecules . Journal of Pharmaceutical Sciences 2006. PMID 16865691
  • Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin. The EMBO Journal 2006. PMID 16871158
  • Selective Inhibition of c-Myc/Max Dimerization and DNA Binding by Small Molecules. Chemistry and Biology 2006. PMID 16873022
  • Small molecule screening in the zebrafish. Methods 2006. PMID 16877005
  • In Vitro Activity of a New Antibacterial Rhodanine Derivative Against Staphylococcus Epidermidis Biofilms. Journal of Antimicrobial Chemotherapy 2006. PMID 16880176
  • Voltage-Gated K+ Channel Block by Catechol Derivatives: Defining Nonselective and Selective Pharmacophores . Journal of Pharmacology and Experimental Therapeutics 2006. PMID 16880198
  • Searching for New Antimalarial Therapeutics Amongst Known Drugs. Chemical Biology and Drug Design 2006. PMID 16882315
  • Discovery and characterization of inhibitors of human palmitoyl acyltransferases. Molecular Cancer Therapeutics 2006. PMID 16891450
  • Exogenous control of mammalian gene expression via modulation of translational termination. Nature Medicine 2006. PMID 16892063
  • The FRB Domain of mTOR: NMR Solution Structure and Inhibitor Design. Biochemistry 2006. PMID 16922504
  • Initiation of Protein Synthesis by Hepatitis C Virus Is Refractory to Reduced eIF2 GTP Met-tRNAi Met Ternary Complex Availability. Molecular Biology of the Cell 2006. PMID 16928960
  • Two Approaches to Drug Discovery in SOD1-mediated ALS. Journal of Biomolecular Screening 2006. PMID 16928982
  • Chemical Probes of UDP-Galactopyranose Mutase. Chemistry and Biology 2006. PMID 16931332
  • Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy. Nature Chemical Biology 2006. PMID 16936720
  • Thermodynamics of Binding of a Low-Molecular-Weight CD4 Mimetic to HIV-1 gp120 . Biochemistry 2006. PMID 16953583
  • Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion . Proceedings of the National Academy of Sciences 2006. PMID 16963566
  • Treatment of Chlamydia trachomatis with a small molecule inhibitor of the Yersinia type III secretion system disrupts progression of the chlamydial developmental cycle. Molecular Microbiology 2006. PMID 16968227
  • Discovery of Antiglioma Activity of Biaryl 1,2,3,4-Tetrahydroisoquinoline Derivatives and Conformationally Flexible Analogues. Journal of Medicinal Chemistry 2006. PMID 16970409
  • Small molecules with antimicrobial activity against E. coli and P. aeruginosa identified by high-throughput screening. British Journal of Pharmacology 2006. PMID 16981005
  • Multiple Large Filament Bundles Observed in Caulobacter Crescentus by Electron Cryotomography. Molecular Microbiology 2006. PMID 16987173
  • A Fast Clustering Algorithm for Analyzing Highly Similar Compounds of Very Large Libraries. Journal of Chemical Information and Modeling 2006. PMID 16995722
  • Characterization of ATP-independent ERK inhibitors identified through in silico analysis of the active ERK2 structure. Bioorganic and Medicinal Chemistry Letters 2006. PMID 17000106
  • Leadlikeness and structural diversity of synthetic screening libraries. Molecular Diversity 2006. PMID 17031539
  • Managing, profiling and analyzing a library of 2.6 million compounds gathered from 32 chemical providers. Molecular Diversity 2006. PMID 17031540
  • Pyrrolidine Carboxamides as a Novel Class of Inhibitors of Enoyl Acyl Carrier Protein Reductase from Mycobacterium tuberculosis. Journal of Medicinal Chemistry 2006. PMID 17034137
  • Autocrine Insulin Action Activates Akt and Increases Survival of Isolated Human Islets. Other 2006. PMID 17053882
  • Direct observation of individual endogenous protein complexes in situ by proximity ligation. Nature Methods 2006. PMID 17072308
  • A structurally unrelated mimic of a Pseudomonas aeruginosa acyl-homoserine lactone quorum-sensing signal . Proceedings of the National Academy of Sciences 2006. PMID 17075036
  • A Chemical Genetic Screen for Cell Cycle Inhibitors in Zebrafish Embryos. Chemical Biology and Drug Design 2006. PMID 17105485
  • Caenorhabditis Elegans: A Versatile Platform for Drug Discovery. Select Journal Title 2006. PMID 17109493
  • Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge space?. Malaria Journal 2006. PMID 17112376
  • Prediction of pH-Dependent Aqueous Solubility of Druglike Molecules. Journal of Chemical Information and Modeling 2006. PMID 17125200
  • Automatic and Efficient Decomposition of Two-Dimensional Structures of Small Molecules for Fragment-Based High-Throughput Docking. Journal of Medicinal Chemistry 2006. PMID 17149868
  • Conjugating Berberine to a Multidrug Resistance Pump Inhibitor Creates an Effective Antimicrobial. ACS Chemical Biology 2006. PMID 17168555
  • High-throughput screening of small molecules for bioactivity and target identification in Caenorhabditis elegans. Nature Protocols 2006. PMID 17487175
  • Recent Advances in Drug Discovery Research Using Structure‐Based Virtual Screening Techniques: Examples of Success for Diverse Protein Targets. Book Chapter 2006. PMID N/A
  • Parallel solution-phase synthesis of substituted 2-(1,2,4-triazol-3-yl)benzimidazoles. Tetrahedron Letters 2006. PMID N/A
  • Highly selective substitutions in 2,3-dichloropyrazine. A novel general approach to aloisines. Tetrahedron 2006. PMID N/A
  • Tuning of conductance switching by supramolecular structures. Colloids and Surfaces - All Sections 2006. PMID N/A
  • Abstracts of QSAR-related Publications: Molecular Modeling. Other 2006. PMID N/A
  • Success Stories of Computer‐Aided Design. Book Chapter 2006. PMID N/A
  • Azidosubstituted arylboronic acids: synthesis and Suzuki-Miyaura cross-coupling reactions. Tetrahedron 2006. PMID N/A
  • Microwave-assisted synthesis and transformations of sterically hindered 3-(5-tetrazolyl)pyridines. Tetrahedron 2006. PMID N/A
  • Novel approach to the synthesis of perhydropyrazino[1,2-a]pyrazine derivatives from amino alcohols. Tetrahedron Letters 2006. PMID N/A
  • Abstracts of QSAR-related Publications: Data Base Search & Virtual Screening. Other 2006. PMID
  • Custom Synthesis and Custom Chemicals. Other 2006. PMID
  • Abstracts of QSAR‐related Publications: Multivariate Analysis. Other 2006. PMID
  • Abstracts of QSAR-related Publications: Data Base Search & Virtual Screening. Other 2006. PMID
  • Synthesis of planar chiral ferrocene alcohols as potential dendrimer cores. Other 2006. PMID
  • Transformation of homoallylic alcohol oxides into 3-hydroxytetrahydrofurans in aqueous HClO4. Other 2006. PMID
  • Index. Other 2006. PMID
  • Abstracts of QSAR-related Publications: Multivariate Analysis. Other 2006. PMID
  • A Convenient Synthesis of 4,5-Disubstituted 1,2,4-Triazoles Functionalized in Position 3. Other 2006. PMID
  • Synthesis of fluorine‐18‐labelled 5‐ and 6‐fluoro‐2‐pyridinamine. Journal of Labelled Compounds and Radiopharmaceuticals 2006. PMID
  • Receptor‐based Rational Design: Virtual Screening. Book Chapter 2006. PMID
  • Bis(tetrazolyl)benzenes as ligands in the Suzuki reaction: Promoters or inhibitors?. Other 2006. PMID
  • High-content Screening and Profiling of Drug Activity in an Automated Centrosome-Duplication Assay. ChemBioChem 2005. PMID 15568197
  • Concentrations of dioxins and related compounds in the blood of Fukuoka residents. Chemosphere 2005. PMID 15581936
  • Identification of mosquito sterol carrier protein-2 inhibitors. Journal of Lipid Research 2005. PMID 15627652
  • Beta-Diketo Acid Pharmacophore Hypothesis. 1. Discovery of a Novel Class of HIV-1 Integrase Inhibitors. Journal of Medicinal Chemistry 2005. PMID 15634005
  • Histone deacetylase inhibitors. European Journal of Medicinal Chemistry 2005. PMID 15642405
  • A potent small molecule inhibits polyglutamine aggregation in Huntington�s disease neurons and suppresses neurodegeneration in vivo. Proceedings of the National Academy of Sciences 2005. PMID 15642944
  • ZINC--A Free Database of Commercially Available Compounds for Virtual Screening. Journal of Chemical Information and Modeling 2005. PMID 15667143
  • Assessment of chemical libraries for their druggability. Computational Biology and Chemistry 2005. PMID 15680586
  • In Vivo Drug Discovery in the Zebrafish. Nature Reviews Drug Discovery 2005. PMID 15688071
  • High-throughput Screening Method of Inhibitors That Block the Interaction Between 2 Helical Regions of HIV-1 gp41. Journal of Biomolecular Screening 2005. PMID 15695339
  • A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science 2005. PMID 15705855
  • Genetic and chemical analyses of the action mechanisms of sirtinol in Arabidopsis. Proceedings of the National Academy of Sciences 2005. PMID 15710899
  • Optimization and Validation of a Docking-Scoring Protocol; Application to Virtual Screening for COX-2 Inhibitors. Journal of Medicinal Chemistry 2005. PMID 15715473
  • Binding Site of Activators of the Cystic Fibrosis Transmembrane Conductance Regulator in the Nucleotide Binding Domains. Other 2005. PMID 15719171
  • Regiospecific Oxidation of Naphthalene and Fluorene by Toluene Monooxygenases and Engineered Toluene 4-monooxygenases of Pseudomonas Mendocina KR1. Other 2005. PMID 15723332
  • Selective Small Molecules Blocking HIV-1 Tat and Coactivator PCAF Association. Journal of the American Chemical Society 2005. PMID 15724976
  • Quinone reductase 2 substrate specificity and inhibition pharmacology. Chemico-Biological Interactions 2005. PMID 15733542
  • Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation . Proceedings of the National Academy of Sciences 2005. PMID 15738401
  • Target-family-oriented Focused Libraries for Kinases--Conceptual Design Aspects and Commercial Availability. ChemBioChem 2005. PMID 15742385
  • CHMIS-C: A Comprehensive Herbal Medicine Information System for Cancer. Journal of Medicinal Chemistry 2005. PMID 15743190
  • Discovery of a Novel Class of Reversible Non-Peptide Caspase Inhibitors via a Structure-Based Approach. Journal of Medicinal Chemistry 2005. PMID 15743206
  • Gastrin-releasing peptide (GRP) induces angiogenesis and the specific GRP blocker 77427 inhibits tumor growth in vitro and in vivo. Oncogene 2005. PMID 15750618
  • Analysis of the mKir2.1 channel activity in potassium influx defective Saccharomyces cerevisiae strains determined as changes in growth characteristics. FEBS Letters 2005. PMID 15757667
  • The power of chemical genomics to study the link between endomembrane system components and the gravitropic response. Proceedings of the National Academy of Sciences 2005. PMID 15772170
  • In Vivo Analysis of Phagocytosis of Apoptotic Cells by Testicular Sertoli Cells. Other 2005. PMID 15791597
  • Screening for Cell Migration Inhibitors via Automated Microscopy Reveals a Rho-Kinase Inhibitor. Chemistry and Biology 2005. PMID 15797222
  • Virtual Docking Approaches to Protein Kinase B Inhibition. Journal of Medicinal Chemistry 2005. PMID 15801821
  • Facile Synthesis, Structure, and Luminescence Properties of Pt(diimine)bis(arylacetylide) Chromophore?Donor Dyads. Inorganic Chemistry 2005. PMID 15819547
  • G2 arrest and apoptosis by 2-amino-N-quinoline-8-yl-benzenesulfonamide (QBS), a novel cytotoxic compound. Biochemical Pharmacology 2005. PMID 15826604
  • Malaria Parasites Are Rapidly Killed by Dantrolene Derivatives Specific for the Plasmodial Surface Anion Channel . Molecular Pharmacology 2005. PMID 15843600
  • The Psammaplysenes, Specific Inhibitors of FOXO1a Nuclear Export. Journal of Natural Products 2005. PMID 15844952
  • Small molecule inhibitors specifically targeting type III secretion. Infection and Immunity 2005. PMID 15845518
  • Targeting Tn5 Transposase Identifies Human Immunodeficiency Virus Type 1 Inhibitors. Antimicrobial Agents and Chemotherapy 2005. PMID 15855529
  • Endocytosis is not required for the selective lipid uptake mediated by murine SR-BI. Biochimica et Biophysica Acta 2005. PMID 15866482
  • Current directions in the evolution of compound libraries.. Current Opinion in Drug Discovery and Development 2005. PMID 15892244
  • Novel Genotoxicity Assays Identify Norethindrone to Activate p53 and Phosphorylate H2AX. Carcinogenesis 2005. PMID 15905198
  • Systematic Identification of Antiprion Drugs by High-Throughput Screening Based on Scanning for Intensely Fluorescent Targets. Journal of Virology 2005. PMID 15919931
  • A Small-Molecule Inhibitor of Mps1 Blocks the Spindle-Checkpoint Response to a Lack of Tension on Mitotic Chromosomes. Current Biology 2005. PMID 15936280
  • Diverse Small-Molecule Modulators of SMN Expression Found by High-Throughput Compound Screening: Early Leads Towards a Therapeutic for Spinal Muscular Atrophy. Human Molecular Genetics 2005. PMID 15944201
  • Ultra-short open capillary columns in gas-liquid chromatography. Journal of Chromatography 2005. PMID 15974133
  • Structure-Based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein?Ligand Affinity. Journal of Medicinal Chemistry 2005. PMID 15974586
  • Efficient synthetic inhibitors of anthrax lethal factor . Proceedings of the National Academy of Sciences 2005. PMID 15983377
  • Representing Receptor Flexibility in Ligand Docking through Relevant Normal Modes. Journal of the American Chemical Society 2005. PMID 15984891
  • Identification of N-phenyl-N?-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4. Virology 2005. PMID 15996703
  • Identification of Novel Extracellular Signal-Regulated Kinase Docking Domain Inhibitors. Journal of Medicinal Chemistry 2005. PMID 15999996
  • Polymer-supported synthesis of bicyclic gamma-lactams. Journal of Combinatorial Chemistry 2005. PMID 16004492
  • Discovery and Structure-Activity Relationship of 3-Aryl-5-aryl-1,2,4-oxadiazoles as a New Series of Apoptosis Inducers and Potential Anticancer Agents. Journal of Medicinal Chemistry 2005. PMID 16078840
  • High-throughput Screening of G Protein-Coupled Receptor Antagonists Using a Bioluminescence Resonance Energy Transfer 1-based beta-arrestin2 Recruitment Assay. Journal of Biomolecular Screening 2005. PMID 16093556
  • The small chemical vacuolin-1 alters the morphology of lysosomes without inhibiting Ca2+-regulated exocytosis. EMBO Reports 2005. PMID 16113649
  • Inhibition of the Calcineurin-NFAT Interaction by Small Organic Molecules Reflects Binding at an Allosteric Site. The Journal of Biological Chemistry 2005. PMID 16148011
  • Structure activity relationship study of novel necroptosis inhibitors. Bioorganic and Medicinal Chemistry Letters 2005. PMID 16153840
  • Fast Structure-Based Virtual Ligand Screening Combining FRED, DOCK, and Surflex. Journal of Medicinal Chemistry 2005. PMID 16162004
  • Evaluating the High-Throughput Screening Computations. Journal of Biomolecular Screening 2005. PMID 16170047
  • Experimental Screening of Dihydrofolate Reductase Yields a "Test Set" of 50,000 Small Molecules for a Computational Data-Mining and Docking Competition. Journal of Biomolecular Screening 2005. PMID 16170050
  • Here Be Dragons: Docking and Screening in an Uncharted Region of Chemical Space. Journal of Biomolecular Screening 2005. PMID 16170052
  • JNK1-dependent Antimitotic Activity of Thiazolidin Compounds in Human Non-Small-Cell Lung and Colon Cancer Cells. Other 2005. PMID 16179969
  • Small-Molecule Inhibitor of Vibrio cholerae Virulence and Intestinal Colonization. Science 2005. PMID 16223984
  • Ester Derivatives of Nucleoside Inhibitors of Reverse Transcriptase: II. Molecular Systems for Combined Therapy With 3'-azido-3'-deoxythymidine and 2',3'-didehydro-3'-deoxythymidine. Other 2005. PMID 16245688
  • Small molecules that reactivate p53 in renal cell carcinoma reveal a NF- B-dependent mechanism of p53 suppression in tumors. Proceedings of the National Academy of Sciences 2005. PMID 16287968
  • New Class of Competitive Inhibitor of Bacterial Histidine Kinases. Journal of Bacteriology 2005. PMID 16291694
  • Lead Validation and SAR Development via Chemical Similarity Searching; Application to Compounds Targeting the pY+3 Site of the SH2 Domain of p56lck. Journal of Chemical Information and Modeling 2005. PMID 16309282
  • Identifying Biologically Active Compound Classes Using Phenotypic Screening Data and Sampling Statistics. Journal of Chemical Information and Modeling 2005. PMID 16309290
  • Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1. Journal of Medicinal Chemistry 2005. PMID 16335928
  • 2-(Benzimidazol-2-yl)quinoxalines: A Novel Class of Selective Antagonists at Human A1 and A3 Adenosine Receptors Designed by 3D Database Searching. Journal of Medicinal Chemistry 2005. PMID 16366607
  • Small molecules that delay S phase suppress a zebrafish bmyb mutant. Nature Chemical Biology 2005. PMID 16372403
  • Chemical Inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nature Chemical Biology 2005. PMID 16408008
  • Application of a Neural Network for the Prediction of Crystallization Kinetics. Industrial and Engineering Chemistry Research 2005. PMID N/A
  • Enantioselective Synthesis of Beta-Amino Acids. Journal of the American Chemical Society 2005. PMID N/A
  • The first preparation of (1S,5R)-(-)- and (1R,5S)-(+)-7-phenyl-3-borabicyclo[3.3.1]non-6-enes and their application for synthesis of chiral cyclohexene derivatives. Journal of Organometallic Chemistry 2005. PMID N/A
  • Preparation and Properties of Polyacrylate/Clay Photocured Nanocomposite Materials. Chemistry of Materials 2005. PMID N/A
  • Highly selective mono-substitution in Pd-catalyzed cross-coupling reactions of 3,6-dichloropyridazine with organozinc compounds. Tetrahedron Letters 2005. PMID N/A
  • Intramolecular [2+3]-addition of an azide to a CC double bond as a novel approach to piperazines. Tetrahedron Letters 2005. PMID N/A
  • Transition Metal Catalyzed [2+2+2] Cycloaddition and Application in Organic Synthesis. European Journal of Organic Chemistry 2005. PMID
  • Compound Selection and Filtering in Library Design. Other 2005. PMID
  • Literature Highlights in Combinatorial Science: QSAR Comb. Sci. 7/2005. Other 2005. PMID
  • Abstracts of QSAR‐related Publications 6/2005. Other 2005. PMID
  • Strategies for Targeting Protein–Protein Interactions With Synthetic Agents. Angewandte Chemie 2005. PMID
  • Chemoinformatic Tools for Library Design and the Hit‐to‐Lead Process: A User's Perspective. Book Chapter 2005. PMID