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2009-2010 Research Articles Citing ChemBridge

Below is a partial list of articles citing the use of ChemBridge libraries and compounds. The list is updated as additional articles are identified. The PMID value can be used to link to the record at the PubMed website.

• A visible wavelength spectrophotometric assay suitable for high-throughput screening of 3-hydroxy-3-methylglutaryl-CoA synthase. Analytical Biochemistry 2010. PMID 19706283
• A nonradioactive iodide uptake assay for sodium iodide symporter function. Analytical Biochemistry 2010. PMID 19733144
• Interaction of benzopyranone derivatives and related compounds with human concentrative nucleoside transporters 1, 2 and 3 heterologously expressed in porcine PK15 nucleoside transporter deficient cells. Structure-activity relationships and determinants of. Biochemical Pharmacology 2010. PMID 19735647
• Site-directed Fragment-Based Generation of Virtual Sialic Acid Databases Against Influenza A Hemagglutinin. Other 2010. PMID 19856192
• Identification of ([beta]-carboxyethyl)-rhodanine derivatives exhibiting peroxisome proliferator-activated receptor gamma activity. European Journal of Medicinal Chemistry 2010. PMID 19879669
• Structural Studies of Pterin-Based Inhibitors of Dihydropteroate Synthase. Journal of Medicinal Chemistry 2010. PMID 19899766
• Quantitative Analyses of Aggregation, Autofluorescence, and Reactivity Artifacts in a Screen for Inhibitors of a Thiol Protease. Journal of Medicinal Chemistry 2010. PMID 19908840
• Identification and characterization of small compound inhibitors of human FATP2. Biochemical Pharmacology 2010. PMID 19913517
• Antiplasmodial activity of piperazine sulfonamides. Bioorganic and Medicinal Chemistry Letters 2010. PMID 19914069
• Converse modulation of toxic [alpha]-synuclein oligomers in living cells by N\'-benzylidene-benzohydrazide derivates and ferric iron. Biochemical and Biophysical Research Communications 2010. PMID 19914207
• Novel Organic Proteasome Inhibitors Identified by Virtual and in Vitro Screening. Journal of Medicinal Chemistry 2010. PMID 19919035
• Sirtuins inhibitors: The approach to affinity and selectivity. Biochimica et Biophysica Acta 2010. PMID 19931429
• Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase. European Journal of Medicinal Chemistry 2010. PMID 19939518
• High glucose stimulates macrophage SR-BI expression and induces a switch in its activity from cholesterol efflux to cholesterol influx. Biochemical and Biophysical Research Communications 2010. PMID 19941833
• Rationalizing the chemical space of protein-protein interaction inhibitors. Drug Discovery Today 2010. PMID 19969101
• Identification of triazinoindol-benzimidazolones as nanomolar inhibitors of the Mycobacterium tuberculosis enzyme TDP-6-deoxy-d-xylo-4-hexopyranosid-4-ulose 3,5-epimerase (RmlC). Bioorganic and Medicinal Chemistry Journal 2010. PMID 19969466
• Identification, Synthesis, and Pharmacological Evaluation of Tetrahydroindazole Based Ligands as Novel Antituberculosis Agents. Journal of Medicinal Chemistry 2010. PMID 20000470
• Roles of cutaneous versus spinal TRPA1 channels in mechanical hypersensitivity in the diabetic or mustard oil-treated non-diabetic rat. Neuropharmacology 2010. PMID 20004676
• Identification of small molecule inhibitors of pyruvate kinase M2. Biochemical Pharmacology 2010. PMID 20005212
• Characterization of non-lipid autotaxin inhibitors. Bioorganic and Medicinal Chemistry Journal 2010. PMID 20005724
• Small-molecule tools for dissecting the roles of SSB/protein interactions in genome maintenance . Proceedings of the National Academy of Sciences 2010. PMID 20018747
• Synthesis and antituberculosis activity of novel mefloquine-isoxazole carboxylic esters as prodrugs. Bioorganic and Medicinal Chemistry Letters 2010. PMID 20022500
• Design and synthesis of selective inhibitors of Placental Alkaline Phosphatase. Bioorganic and Medicinal Chemistry Journal 2010. PMID 20031422
• Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase. Journal of Medicinal Chemistry 2010. PMID 20038112
• Optimization of a Pipemidic Acid Autotaxin Inhibitor. Journal of Medicinal Chemistry 2010. PMID 20041668
• Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase.. BMC Cancer 2010. PMID 20055993
• Identification of known drugs that act as inhibitors of NF-[kappa]B signaling and their mechanism of action. Biochemical Pharmacology 2010. PMID 20067776
• Computer-aided drug design and ADMET predictions for identification and evaluation of novel potential farnesyltransferase inhibitors in cancer therapy. Journal of Molecular Graphics and Modelling 2010. PMID 20074987
• The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma.. Blood 2010. PMID 20075161
• Fragmenting the S100B-p53 Interaction: Combined virtual/biophysical Screening Approaches to Identify Ligands. ChemMedChem 2010. PMID 20077460
• Blueprint for antimicrobial hit discovery targeting metabolic networks . Proceedings of the National Academy of Sciences 2010. PMID 20080587
• Enhanced Signaling Downstream of Ribonucleic Acid-activated Protein Kinase-Like Endoplasmic Reticulum Kinase Potentiates Lipotoxic Endoplasmic Reticulum Stress in Human Islets. Other 2010. PMID 20080856
• Rapid behavior-based identification of neuroactive small molecules in the zebrafish. Nature Chemical Biology 2010. PMID 20081854
• In silico studies of blood coagulation proteins: from mosaic proteases to nonenzymatic cofactor inhibitors. Current Opinion in Structural Biology 2010. PMID 20083402
• Improved synthesis of a fluorogenic ceramidase substrate. Bioorganic and Medicinal Chemistry Journal 2010. PMID 20085856
• Structure-Based Discovery of Novel Chemotypes for Adenosine A2A Receptor Antagonists. Journal of Medicinal Chemistry 2010. PMID 20095623
• Drug screening for hearing loss: Using the zebrafish lateral line to screen for drugs that prevent and cause hearing loss. Drug Discovery Today 2010. PMID 20096805
• Novel Inhibitors of Dengue Virus Methyltransferase: Discovery by in Vitro-Driven Virtual Screening on a Desktop Computer Grid. Journal of Medicinal Chemistry 2010. PMID 20108931
• Novel antibacterial compounds specifically targeting the essential WalR response regulator. The Journal of Antibiotics 2010. PMID 20111065
• Discovery of Novel Fibroblast Growth Factor Receptor 1 Kinase Inhibitors by Structure-Based Virtual Screening. Journal of Medicinal Chemistry 2010. PMID 20121196
• SAR and Pharmacophore Models for the Rhodanine Inhibitors of Plasmodium Falciparum Enoyl-Acyl Carrier Protein Reductase. Other 2010. PMID 20131353
• New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays. Journal of Medicinal Chemistry 2010. PMID 20131845
• A broad-spectrum antiviral targeting entry of enveloped viruses. Proceedings of the National Academy of Sciences 2010. PMID 20133606
• Chemical Biology Strategy Reveals Pathway-Selective Inhibitor of NF-kappaB Activation Induced by Protein Kinase C. ACS Chemical Biology 2010. PMID 20141195
• Toward the Rational Design of p53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant. Chemistry and Biology 2010. PMID 20142040
• Identification of a novel chemical potentiator and inhibitors of UCH-L1 by in silico drug screening. Neurochemistry International 2010. PMID 20144674
• Iodine scanning of a phenazine inhibitor of vacuolar sorting. Bioorganic and Medicinal Chemistry Letters 2010. PMID 20153185
• Computational screening for membrane-directed inhibitors of mast cell activation. European Journal of Medicinal Chemistry 2010. PMID 20153565
• Selective benzimidazole inhibitors of the antigen receptor-mediated NF-kappaB activation pathway. Bioorganic and Medicinal Chemistry Journal 2010. PMID 20153655
• Discovery and Characterization of Inhibitors of Pseudomonas aeruginosa Type III Secretion. Antimicrobial Agents and Chemotherapy 2010. PMID 20176902
• Parallel Multiplicative Target Screening against Divergent Bacterial Replicases: Identification of Specific Inhibitors with Broad Spectrum Potential. Biochemistry 2010. PMID 20184361
• Exploration of inhibitors for diaminopimelate aminotransferase. Bioorganic and Medicinal Chemistry Journal 2010. PMID 20185317
• Small Molecule Activators of TRPML3. Chemistry and Biology 2010. PMID 20189104
• Expanding the range of `druggable\' targets with natural product-based libraries: an academic perspective. Current Opinion in Chemical Biology 2010. PMID 20202892
• The discovery of nongenotoxic activators of p53: Building on a cell-based high-throughput screen. Seminars in Cancer Biology Journal 2010. PMID 20206696
• Oxime esters as selective, covalent inhibitors of the serine hydrolase retinoblastoma-binding protein 9 (RBBP9). Bioorganic and Medicinal Chemistry Letters 2010. PMID 20207142
• Post-docking virtual screening of diverse binding pockets: Comparative study using DOCK, AMMOS, X-Score and FRED scoring functions. European Journal of Medicinal Chemistry 2010. PMID 20227800
• Kinetic-based High-Throughput Screening Assay to Discover Novel Classes of Macrophage Migration Inhibitory Factor Inhibitors. Journal of Biomolecular Screening 2010. PMID 20231420
• Novel Gamma-Secretase Inhibitors Uncover a Common Nucleotide-Binding Site in JAK3, SIRT2, and PS1. The FASEB Journal 2010. PMID 20237298
• How to Choose Relevant Multiple Receptor Conformations for Virtual Screening: A Test Case of Cdk2 and Normal Mode Analysis. Other 2010. PMID 20237920
• Drug- and Lead-likeness, Target Class, and Molecular Diversity Analysis of 7.9 Million Commercially Available Organic Compounds Provided by 29 Suppliers. Journal of Chemical Information and Modeling 2010. PMID 20297844
• Small Molecule Screen in Zebrafish and HSC Expansion. Other 2010. PMID 20336531
• Prospective Validation of a Comprehensive in Silico hERG Model and Its Applications to Commercial Compound and Drug Databases. ChemMedChem 2010. PMID 20349498
• Identification of small-molecule inhibitors of ricin and shiga toxin using a cell-based high-throughput screen. Toxicon 2010. PMID 20350563
• The Tert-Butylsulfinamide Lynchpin in Transition-Metal-Mediated Multiscaffold Library Synthesis. Organic Letters 2010. PMID 20356070
• Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as Emerging Target for Novel Analgesics and Anti-Inflammatory Agents. Journal of Medicinal Chemistry 2010. PMID 20356305
• 2D binary QSAR modeling of LPA3 receptor antagonism. Journal of Molecular Graphics and Modelling 2010. PMID 20356772
• Palmitate Induces a Pro-Inflammatory Response in Human Pancreatic Islets That Mimics CCL2 Expression by Beta Cells in Type 2 Diabetes. Other 2010. PMID 20369226
• A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo. Cancer Cell 2010. PMID 20385364
• A High-throughput Pharmacoviral Approach Identifies Novel Oncolytic Virus Sensitizers. Molecular Therapy 2010. PMID 20389287
• Targeting the BH3 Domain Mediated Protein-Protein Interaction of Bcl-xL through Virtual Screening. Journal of Chemical Information and Modeling 2010. PMID 20392095
• Fragment-based Lead Discovery: Screening and Optimizing Fragments for Thermolysin Inhibition. ChemMedChem 2010. PMID 20394106
• Are There Differences between Launched Drugs, Clinical Candidates, and Commercially Available Compounds?. Journal of Chemical Information and Modeling 2010. PMID 20394396
• Inhibition of Retrograde Transport Protects Mice from Lethal Ricin Challenge. Cell 2010. PMID 20403321
• Structure-Based Discovery of A2A Adenosine Receptor Ligands. Journal of Medicinal Chemistry 2010. PMID 20405927
• Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents. Journal of Clinical Investigation 2010. PMID 20407211
• Small molecule modulation of HH-GLI signaling: Current leads, trials and tribulations. Biochemical Pharmacology 2010. PMID 20412786
• Identification of Metabotropic Glutamate Receptor Subtype 5 Potentiators Using Virtual High-Throughput Screening. ACS Chemical Neuroscience 2010. PMID 20414370
• Utilization of an In Vivo Reporter for High Throughput Identification of Branched Small Molecule Regulators of Hypoxic Adaptation. Chemistry and Biology 2010. PMID 20416509
• Novel SHP-1 Inhibitors Tyrosine Phosphatase Inhibitor-1 and Analogs with Preclinical Anti-Tumor Activities as Tolerated Oral Agents. Journal of Immunology 2010. PMID 20421638
• Virtual screening, selection and development of a benzindolone structural scaffold for inhibition of lumazine synthase. Bioorganic and Medicinal Chemistry Journal 2010. PMID 20430628
• 4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide (CMH) Targets mRNA of the c-FLIP Variants and Induces Apoptosis in MCF-7 Human Breast Cancer Cells. Other 2010. PMID 20446019
• Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation. Proceedings of the National Academy of Sciences 2010. PMID 20457929
• Inhibition of Protein Kinase C-Driven Nuclear Factor-KappaB Activation: Synthesis, Structure-Activity Relationship, and Pharmacological Profiling of Pathway Specific Benzimidazole Probe Molecules. Journal of Medicinal Chemistry 2010. PMID 20481485
• Identification of Translational Activators of Glial Glutamate Transporter EAAT2 Through Cell-Based High-Throughput Screening: An Approach to Prevent Excitotoxicity. Journal of Biomolecular Screening 2010. PMID 20508255
• Identification of influenza A nucleoprotein as an antiviral target. Nature Biotechnology 2010. PMID 20512121
• A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans. Nature Chemical Biology 2010. PMID 20512140
• Tautomerism in Large Databases. Other 2010. PMID 20512400
• Sterol carrier protein-x gene and effects of sterol carrier protein-2 inhibitors on lipid uptake in Manduca sexta.. BMC Physiology 2010. PMID 20534138
• Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor. Chemistry and Biology 2010. PMID 20534345
• Characterization of apoA-I-dependent Lipid Efflux From Adipocytes and Role of ABCA1. Other 2010. PMID 20535530
• Complementarity Between a Docking and a High-Throughput Screen in Discovering New Cruzain Inhibitors. Journal of Medicinal Chemistry 2010. PMID 20540517
• Small molecule screening in zebrafish: an in vivo approach to identifying new chemical tools and drug leads.. Cell Communication and Signaling 2010. PMID 20540792
• Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay. Antimicrobial Agents and Chemotherapy 2010. PMID 20547797
• Use of a 1H-benzoimidazole derivative as an n-type dopant and to enable air-stable solution-processed n-channel organic thin-film transistors.. Journal of the American Chemical Society 2010. PMID 20552967
• Derivatives of Salicylic Acid as Inhibitors of YopH in Yersinia Pestis. Chemical Biology and Drug Design 2010. PMID 20560978
• Synthesis and Biological Evaluation of Analogues of a Novel Inhibitor of Beta-Amyloid Secretion. Journal of Medicinal Chemistry 2010. PMID 20568779
• A Novel Pharmacophore Model for the Design of Anthrax Lethal Factor Inhibitors. Chemical Biology and Drug Design 2010. PMID 20572812
• Inhibition of Eimeria Tenella CDK-related Kinase 2: From Target Identification to Lead Compounds. ChemMedChem 2010. PMID 20575139
• The Pthaladyns: GTP Competitive Inhibitors of Dynamin I and II GTPase Derived from Virtual Screening. Journal of Medicinal Chemistry 2010. PMID 20575553
• Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase. Nature Biotechnology 2010. PMID 20581845
• Chemo-nociceptive Signalling From the Colon Is Enhanced by Mild Colitis and Blocked by Inhibition of Transient Receptor Potential Ankyrin 1 Channels. British Journal of Pharmacology 2010. PMID 20590633
• Discovery of a Proneurogenic, Neuroprotective Chemical. Cell 2010. PMID 20603013
• Functional Identification and Structure Determination of Two Novel Prolidases from cog1228 in the Amidohydrolase Superfamily,. Biochemistry 2010. PMID 20604542
• Fragment-based Discovery of Novel Thymidylate Synthase Leads by NMR Screening and Group Epitope Mapping. Chemical Biology and Drug Design 2010. PMID 20626411
• CH223191 Is a Ligand-Selective Antagonist of the Ah (Dioxin) Receptor. Toxicological Sciences 2010. PMID 20634293
• Discovery and Mechanistic Study of a Class of Protein Arginine Methylation Inhibitors. Journal of Medicinal Chemistry 2010. PMID 20666457
• Effects of Mutations in Aedes aegypti Sterol Carrier Protein-2 on the Biological Function of the Protein. Biochemistry 2010. PMID 20681612
• Integration of Small-Molecule Discovery in Academic Biomedical Research. Other 2010. PMID 20687180
• Discovery of New Inhibitors of Schistosoma mansoni PNP by Pharmacophore-Based Virtual Screening. Journal of Chemical Information and Modeling 2010. PMID 20695479
• Postprocessing of Protein-Ligand Docking Poses Using Linear Response MM-PB/SA: Application to Wee1 Kinase Inhibitors. Journal of Chemical Information and Modeling 2010. PMID 20712342
• Species-Dependent Degradation of Ciprofloxacin in a Membrane Anodic Fenton System. Journal of Agricultural and Food Chemistry 2010. PMID 20726585
• Identification and mechanism of ABA receptor antagonism. Nature Structural and Molecular Biology 2010. PMID 20729862
• A small-molecule screen identifies new functions for the plant hormone strigolactone. Nature Chemical Biology 2010. PMID 20818397
• Enhancement of proteasome activity by a small-molecule inhibitor of USP14. Nature 2010. PMID 20829789
• Discovery of Novel Cyclophilin A Ligands Using an H/D Exchange- And Mass Spectrometry-Based Strategy. Journal of Biomolecular Screening 2010. PMID 20855564
• Acetylation of tau inhibits its degradation and contributes to tauopathy. Neuron 2010. PMID 20869593
• Stabilization of Mutant p53 via Alkylation of Cysteines and Effects on DNA Binding. Protein Science 2010. PMID 20878668
• High-throughput Screen for Escherichia Coli Heat Shock Protein 70 (Hsp70/DnaK): ATPase Assay in Low Volume by Exploiting Energy Transfer. Journal of Biomolecular Screening 2010. PMID 20926844
• A Real-Time Screening Assay for GIRK1/4 Channel Blockers. Journal of Biomolecular Screening 2010. PMID 20938046
• Transient receptor potential ankyrin 1: emerging pharmacology and indications for cardiovascular biology.. Acta Physiologica 2010. PMID 20950342
• Discovery of a Novel Chemical Class of mGlu5 Allosteric Ligands with Distinct Modes of Pharmacology. ACS Chemical Neuroscience 2010. PMID 20981342
• Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains. Proceedings of the National Academy of Sciences 2010. PMID 21041639
• Virtual Screening to Identify Novel Antagonists for the G Protein-Coupled NK3 Receptor. Journal of Medicinal Chemistry 2010. PMID 21047106
• Inhibitors of the Salicylate Synthase (MbtI) From Mycobacterium Tuberculosis Discovered by High-Throughput Screening. ChemMedChem 2010. PMID 21053346
• Insights into Nucleotide Recognition by Cell Division Protein FtsZ from a mant-GTP Competition Assay and Molecular Dynamics. Biochemistry 2010. PMID 21058659
• Structural determinants of PERK inhibitor potency and selectivity. Chemical Biology and Drug Design 2010. PMID 21070610
• Discovery of Non-Glycoside Sodium-Dependent Glucose Co-Transporter 2 (SGLT2) Inhibitors by Ligand-Based Virtual Screening. Journal of Medicinal Chemistry 2010. PMID 21090651
• Xenoestrogens regulate the activity of arginine methyltransferases.. ChemBioChem 2010. PMID 21243720
• Selective GPR35 Antagonists - Probes 1 & 2. Probe Reports from the NIH Molecular Libraries Program 2010. PMID 21433393
• A Potent and Selective Inhibitor of Cdc42 GTPase. Probe Reports from the NIH Molecular Libraries Program 2010. PMID 21433396
• High-throughput Screening of Viral Entry Inhibitors Using Pseudotyped Virus. Current Protocols in Pharmacology 2010. PMID 21935898
• Screening for Selective Ligands for GPR55 - Antagonists. Probe Reports from the NIH Molecular Libraries Program 2010. PMID 22091481
• Static Biofilm Cultures of Gram-positive Pathogens Grown in a Microtiter Format Used for Anti-Biofilm Drug Discovery. Current Protocols in Pharmacology 2010. PMID 22294365
• Academic screening goes high-throughput. Nature Methods 2010. PMID N/A
• Preparation and characterization of UV-curable organic/inorganic hybrid composites for NIR cutoff and antistatic coatings. Journal of Applied Polymer Science 2010. PMID N/A
• Novel fragment-like inhibitors of EphA2 obtained by experimental screening and modelling. Mendeleev Communications 2010. PMID N/A
• Preparation and characterizations of highly transparent UV-curable ZnO-acrylic nanocomposites. Ceramics International Journal 2010. PMID N/A
• Formation of oxidized products from the reaction of gaseous phenanthrene with the OH radical in a reaction chamber. Atmospheric Environment 2010. PMID N/A
• Design, synthesis, evaluation and QSAR analysis of N1-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitors. Bioorganic and Medicinal Chemistry Letters 2010. PMID N/A
• Design and synthesis of N-vinylacetamide derivative with bulky group by nucleophilic substitution reaction. Journal of Molecular Structure 2010. PMID N/A
• International symposium “Advanced Science in Organic Chemistry” (ASOC-CRIMEA 2010). Other 2010. PMID
• Asia Federation Report on International Symposium on Grid Computing (ISGC) 2010. Other 2010. PMID
• In Silico ADME/Tox Predictions. Book Chapter 2010. PMID
• In Vitro Screening: Screening by Nuclear Magnetic Resonance. Book Chapter 2010. PMID
• A Drug Screen in Zebrafish Identifies a New Therapeutic Agent Active in Acute Lymphoblastic Leukemia. Blood 2010. PMID
• The development of an FIA-CD strategy for screening sulfated polysaccharides using antimalarial drugs and related species as probes. Other 2010. PMID
• Receptor Targets in Drug Discovery. Other 2010. PMID
• Synthesis and circular dichroism of the optically active dendrimers with the planar chiral ferrocene core. Other 2010. PMID
• Mining Natural Product-Derived Molecules Against Cancer Targets: The Case of the Androgen Receptor in Prostate Cancer. Book Chapter 2010. PMID
• In Vitro Test for Potential Inhibitors of Plasmepsin II and IV as Anti-malarial Agents. Book Chapter 2010. PMID
• Poster Session 3 (PO3-01 to PO3-171). Heart Rhythm 2010. PMID
• Targeting mitochondria for cancer therapy. Other 2010. PMID
• Preparation and characterizations of tantalum pentoxide (Ta2O5) nanoparticles and UV‐curable Ta2O5‐acrylic nanocomposites. Journal of Applied Polymer Science 2010. PMID
• A road less traveled by: Exploring a decade of Ellman chemistry. Bioorganic and Medicinal Chemistry Journal 2009. PMID 18343129
• High throughput screening of potentially selective MMP-13 exosite inhibitors utilizing a triple-helical FRET substrate. Bioorganic and Medicinal Chemistry Journal 2009. PMID 18358729
• Ranking the selectivity of PubChem screening hits by activity-based protein profiling: MMP13 as a case study. Bioorganic and Medicinal Chemistry Journal 2009. PMID 18364257
• LDLs stimulate p38 mitogen-activated kinases and wound healing through the class B type 1 scavenger receptor independently of Ras and PI3 kinase . Journal of Lipid Research 2009. PMID 18757346
• 2-bromopalmitate and 2-(2-Hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro. Journal of Lipid Research 2009. PMID 18827284
• Role for chlamydial type III secretion apparatus in host cytokine expression . Infection and Immunity 2009. PMID 18852236
• High-throughput assays probing protein-RNA interactions of eukaryotic translation initiation factors. Analytical Biochemistry 2009. PMID 18926791
• Complement 1s is the serine protease that cleaves IGFBP-5 in human osteoarthritic joint fluid. Osteoarthritis and Cartilage Journal 2009. PMID 18930415
• Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis. American Journal of Physiology - Gastrointestinal and Liver Physiology 2009. PMID 18974311
• Dynasore, a Dynamin Inhibitor, Induces PAI-1 Expression in MeT-5A Human Pleural Mesothelial Cells. American Journal of Respiratory Cell and Molecular Biology 2009. PMID 18978303
• Chemical Biology Investigation of Cell Death Pathways Activated by Endoplasmic Reticulum Stress Reveals Cytoprotective Modulators of ASK1*. Journal of Biological Chemistry 2009. PMID 19004820
• Selective activation of apoptosis by a novel set of 4-aryl-3-(3-aryl-1-oxo-2-propenyl)-2(1H)-quinolinones through a Myc-dependent pathway. Cancer Letters 2009. PMID 19008038
• Targeting Type III Secretion in Yersinia pestis. Antimicrobial Agents and Chemotherapy 2009. PMID 19015348
• TRPA1 in Bradykinin-induced Mechano-hypersensitivity of Vagal C Fibers in Guinea Pig Esophagus. American Journal of Physiology - Gastrointestinal and Liver Physiology 2009. PMID 19033534
• Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity. Molecular Pharmacology 2009. PMID 19047481
• Crystal structures of rat catechol-O-methyltransferase complexed with coumarine-based inhibitor. Biochemical and Biophysical Research Communications 2009. PMID 19056347
• Characterization of small-molecule inhibitors of the sodium iodide symporter. Journal of Endocrinology 2009. PMID 19066290
• Double-Stranded RNA-Dependent Protein Kinase (PKR)-Dependent Apoptosis Induction by a Novel Small Compound. Journal of Pharmacology and Experimental Therapeutics 2009. PMID 19066342
• Differential sensitivities of CaV1.2 IIS5-S6 mutants to 1,4-dihydropyridine analogs. European Journal of Pharmacology 2009. PMID 19068212
• Synthesis and Evaluation of Novel Inhibitors of Pim-1 and Pim-2 Protein Kinases. Journal of Medicinal Chemistry 2009. PMID 19072652
• The Use of Chemical Genomics to Investigate Pathways Intersecting Auxin-Dependent Responses and Endomembrane Trafficking in Arabidopsis Thaliana. Other 2009. PMID 19085151
• Virtual Screening and Biological Characterization of Novel Histone Arginine Methyltransferase PRMT1 Inhibitors. ChemMedChem 2009. PMID 19085993
• Pannexin-1-dependent caspase-1 Activation and Secretion of IL-1beta Is Regulated by Zinc. Other 2009. PMID 19130485
• Discovery of the First Selective Inhibitor of Excitatory Amino Acid Transporter Subtype 1. Journal of Medicinal Chemistry 2009. PMID 19161278
• ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells. Proceedings of the National Academy of Sciences 2009. PMID 19164757
• Sensing of Dietary Lipids by Enterocytes: A New Role for SR-BI/CLA-1. PLoS ONE 2009. PMID 19169357
• In Silico Screening for PTPN22 Inhibitors: Active Hits From an Inactive Phosphatase Conformation. ChemMedChem 2009. PMID 19177473
• High-throughput Screening for Small-Molecule Inhibitors of LARG-stimulated RhoA Nucleotide Binding via a Novel Fluorescence Polarization Assay. Journal of Biomolecular Screening 2009. PMID 19196702
• A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase. Journal of Biological Chemistry 2009. PMID 19203993
• Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1). Molecular Cancer Therapeutics 2009. PMID 19208825
• Discovery of Novel Myc-Max Heterodimer Disruptors with a Three-Dimensional Pharmacophore Model. Journal of Medicinal Chemistry 2009. PMID 19215087
• Corrected structure of mirin, a small-molecule inhibitor of the Mre11-Rad50-Nbs1 complex. Nature Chemical Biology 2009. PMID 19219009
• Receptor Complementation and Mutagenesis Reveal SR-BI as an Essential HCV Entry Factor and Functionally Imply Its Intra- and Extra-Cellular Domains. PLoS Pathogens 2009. PMID 19229312
• AR Inhibitors Identified by High-Throughput Microscopy Detection of Conformational Change and Subcellular Localization. ACS Chemical Biology 2009. PMID 19236099
• Identification of Three Classes of Heteroaromatic Compounds with Activity against Intracellular Trypanosoma cruzi by Chemical Library Screening. PLoS Neglected Tropical Diseases 2009. PMID 19238193
• Identification of thieno[3,2-b]pyrrole Derivatives as Novel Small Molecule Inhibitors of Neurotropic Alphaviruses. The Journal of Infectious Diseases 2009. PMID 19239364
• Virtual screening to identify lead inhibitors for bacterial NAD synthetase (NADs). Bioorganic and Medicinal Chemistry Letters 2009. PMID 19249205
• Synthesis, Anticancer, and Anti-Inflammatory Activity Evaluation of Methanesulfonamide and Amidine Derivatives of 3,4-diaryl-2-imino-4-thiazolines. Molecular Diversity 2009. PMID 19267213
• Histone deacetylase inhibitors that target tubulin. Cancer Letters 2009. PMID 19268440
• Chemical Probes that Competitively and Selectively Inhibit Stat3 Activation. Public Library of Science 2009. PMID 19274102
• Discovery and Binding Studies on a Series of Novel Pin1 Ligands. Chemical Biology and Drug Design 2009. PMID 19291099
• Development of a Novel Virtual Screening Cascade Protocol to Identify Potential Trypanothione Reductase Inhibitors. Journal of Medicinal Chemistry 2009. PMID 19296695
• Diallyl sulfides in garlic activate both TRPA1 and TRPV1. Biochemical and Biophysical Research Communications 2009. PMID 19298793
• The Synthetic Elicitor 3,5-Dichloroanthranilic Acid Induces NPR1-Dependent and NPR1-Independent Mechanisms of Disease Resistance in Arabidopsis. Plant Physiology 2009. PMID 19304930
• Molecular docking and ligand specificity in fragment-based inhibitor discovery. Nature Chemical Biology 2009. PMID 19305397
• In vivo Imaging of Cutaneous T-Cell Lymphoma Migration to the Skin (Priority Report). Cancer Research 2009. PMID 19318575
• Inhibition of Furin/Proprotein convertase-catalyzed surface and itracellular processing by small molecules. Journal of Biological Chemistry 2009. PMID 19332539
• Large-scale Small-Molecule Screen Using Zebrafish Embryos. Other 2009. PMID 19347615
• K858, a Novel Inhibitor of Mitotic Kinesin Eg5 and Antitumor Agent, Induces Cell Death in Cancer Cells. Cancer Research 2009. PMID 19351824
• Identification of inhibitors of N5-carboxyaminoimidazole ribonucleotide synthetase by high-throughput screening. Bioorganic and Medicinal Chemistry Journal 2009. PMID 19362848
• Unique ligand selectivity of the GPR92/LPA5 lysophosphatidate receptor indicates role in human platelet activation.. Journal of Biological Chemistry 2009. PMID 19366702
• CD36-mediated cholesterol efflux is associated with PPARgamma activation via a MAPK-dependent COX-2 pathway in macrophages. Journal of Cardiovascular Disease Research 2009. PMID 19377069
• A Mammalian Cell-Based Assay for Screening Inhibitors of RNA Cleavage. Other 2009. PMID 19381571
• A Simple, Universal Colorimetric Assay for Endonuclease/Methyltransferase Activity and Inhibition Based on an Enzyme-Responsive Nanoparticle System. ACS Nano 2009. PMID 19402659
• Human macrophage cholesterol efflux potential is enhanced by HDL-associated 17[beta]-estradiol fatty acyl esters. The Journal of Steroid Biochemistry and Molecular Biology 2009. PMID 19406243
• Miogadial and miogatrial with [alpha],[beta]-unsaturated 1,4-dialdehyde moieties--Novel and potent TRPA1 agonists. Life Sciences 2009. PMID 19409911
• Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1. Seminars in Cancer Biology Journal 2009. PMID 19414071
• In Vivo Enhancement of Peptide Display by MHC Class II Molecules with Small Molecule Catalysts of Peptide Exchange1. The Journal of Immunology 2009. PMID 19414787
• TRPA1 in Mast Cell Activation-induced Long-lasting Mechanical Hypersensitivity of Vagal Afferent C fibers in Guinea Pig Esophagus.. American Journal of Physiology - Gastrointestinal and Liver Physiology 2009. PMID 19423751
• From fragment to clinical candidate--a historical perspective. Drug Discovery Today 2009. PMID 19427404
• wwLigCSRre: a 3D ligand-based server for hit identification and optimization. Nucleic Acids Research 2009. PMID 19429687
• Multiple Independent Binding Sites for Small-Molecule Inhibitors on the Oncoprotein c-Myc. Journal of the American Chemical Society 2009. PMID 19432426
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